Roux-en-Y gastric bypass versus calorie restriction: support for surgery per se as the direct contributor to altered responses of insulin and incretins to a mixed meal
J Berggren, A Lindqvist, J Hedenbro, L Groop… - Surgery for Obesity and …, 2017 - Elsevier
Objective To study the immediate effects of Roux-en-Y gastric bypass (RYGB) on glucose
homeostasis, insulin, and incretin responses to mixed-meal tests compared with the effects
of calorie restriction (CR). Setting University-affiliated bariatric surgery clinic. Background
RYGB induces remission of type 2 diabetes (T2D) long before significant weight loss occurs.
The time course and underlying mechanisms of this remission remain enigmatic. A
prevailing theory is that secretory patterns of incretin hormones are altered due to …
homeostasis, insulin, and incretin responses to mixed-meal tests compared with the effects
of calorie restriction (CR). Setting University-affiliated bariatric surgery clinic. Background
RYGB induces remission of type 2 diabetes (T2D) long before significant weight loss occurs.
The time course and underlying mechanisms of this remission remain enigmatic. A
prevailing theory is that secretory patterns of incretin hormones are altered due to …
