Angiogenesis and vascular endothelial growth factor-A expression associated with inflammation in pediatric Crohn's disease
JL Knod, K Crawford, M Dusing, MH Collins… - Journal of …, 2016 - Elsevier
Abstract Background and Aims Angiogenesis is a component of chronic inflammatory
diseases including inflammatory bowel disease. Some studies describe increased
angiogenesis associated with acute disease in adult Crohn's disease and ulcerative colitis,
while animal models aid investigations of mechanism and pathophysiology of angiogenesis.
We aim to explore the role of angiogenesis and its pathways in pediatric Crohn's disease.
Methods Surgical specimens were obtained from pediatric Crohn's disease (both inflamed …
diseases including inflammatory bowel disease. Some studies describe increased
angiogenesis associated with acute disease in adult Crohn's disease and ulcerative colitis,
while animal models aid investigations of mechanism and pathophysiology of angiogenesis.
We aim to explore the role of angiogenesis and its pathways in pediatric Crohn's disease.
Methods Surgical specimens were obtained from pediatric Crohn's disease (both inflamed …