Histopathologic Features of Cutaneous Acute Graft-Versus-Host Disease in T-Cell–Depleted Peripheral Blood Stem Cell Transplant Recipients
A Fischer, AA Jakubowski, ME Lacouture… - The American Journal …, 2015 - journals.lww.com
T-cell–depleted (TCD) allogeneic hematopoietic stem cell transplantation demonstrates
similar efficacy and reduced incidence and severity of graft-versus-host disease (GVHD) in
appropriately selected patients versus T-cell–replete transplantation. The histopathology of
cutaneous acute GVHD (aGVHD) after TCD peripheral blood stem cell transplants (PBSCTs)
is not described. We identified 13 cases of patients after TCD PBSCT, with definitive aGVHD,
and 20 cases of non-aGVHD skin rash in patients after TCD PBSCT, during multidisciplinary …
similar efficacy and reduced incidence and severity of graft-versus-host disease (GVHD) in
appropriately selected patients versus T-cell–replete transplantation. The histopathology of
cutaneous acute GVHD (aGVHD) after TCD peripheral blood stem cell transplants (PBSCTs)
is not described. We identified 13 cases of patients after TCD PBSCT, with definitive aGVHD,
and 20 cases of non-aGVHD skin rash in patients after TCD PBSCT, during multidisciplinary …