Regulatory T-cell therapy for transplantation: how many cells do we need?
Q Tang, K Lee - Current opinion in organ transplantation, 2012 - journals.lww.com
Q Tang, K Lee
Current opinion in organ transplantation, 2012•journals.lww.comIt is feasible to grow human alloantigen-reactive Tregs up to billions, an optimal number to
achieve therapeutic efficacy. Better understanding of Treg lineage commitment and further
technological investments are needed to ease the implementation and ensure consistency
in Treg manufacturing.
achieve therapeutic efficacy. Better understanding of Treg lineage commitment and further
technological investments are needed to ease the implementation and ensure consistency
in Treg manufacturing.
Summary
It is feasible to grow human alloantigen-reactive Tregs up to billions, an optimal number to achieve therapeutic efficacy. Better understanding of Treg lineage commitment and further technological investments are needed to ease the implementation and ensure consistency in Treg manufacturing.
Lippincott Williams & Wilkins