GPR15: a tale of two species

J Bilsborough, JL Viney - Nature Immunology, 2015 - nature.com
Nature Immunology, 2015nature.com
The chemoattractant receptor GPR15 directs the homing of T cells to the colon; however,
GRP15 expression differs in the effector and regulatory T cell subsets of humans versus
those of mice. These findings have profound implications for the potential targeting of
GRP15 for therapeutic intervention.
The chemoattractant receptor GPR15 directs the homing of T cells to the colon; however, GRP15 expression differs in the effector and regulatory T cell subsets of humans versus those of mice. These findings have profound implications for the potential targeting of GRP15 for therapeutic intervention.
nature.com