Chemoprevention of basal and squamous cell carcinoma with a single course of fluorouracil, 5%, cream: a randomized clinical trial

MA Weinstock, SS Thwin, JA Siegel… - JAMA …, 2018 - jamanetwork.com
Importance Keratinocyte carcinoma (ie, cutaneous basal and squamous cell carcinoma) is
the most common cancer in the United States. Objective To determine whether topical
fluorouracil could prevent surgically treated keratinocyte carcinoma. Design, Setting, and
Participants The Veterans Affairs Keratinocyte Carcinoma Chemoprevention Trial was a
randomized, double-blind, placebo-controlled trial of topical fluorouracil for
chemoprevention of keratinocyte carcinoma. Participants were recruited from May 2009 to …