Implication of microRNAs in drug resistance for designing novel cancer therapy
FH Sarkar, Y Li, Z Wang, D Kong, S Ali - Drug resistance updates, 2010 - Elsevier
Recently, microRNAs (miRNAs) have received increasing attention in the field of cancer
research. miRNAs play important roles in many normal biological processes; however, the
aberrant miRNA expression and its correlation with the development and progression of
cancers is an emerging field. Therefore, miRNAs could be used as biomarkers for diagnosis
of cancer and prediction of prognosis. Importantly, some miRNAs could regulate the
formation of cancer stem cells and the acquisition of epithelial–mesenchymal transition …
research. miRNAs play important roles in many normal biological processes; however, the
aberrant miRNA expression and its correlation with the development and progression of
cancers is an emerging field. Therefore, miRNAs could be used as biomarkers for diagnosis
of cancer and prediction of prognosis. Importantly, some miRNAs could regulate the
formation of cancer stem cells and the acquisition of epithelial–mesenchymal transition …