Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine

RJ Young, RM Beams, K Carter, HAR Clark… - Bioorganic & medicinal …, 2000 - Elsevier
RJ Young, RM Beams, K Carter, HAR Clark, DM Coe, CL Chambers, PI Davies, J Dawson…
Bioorganic & medicinal chemistry letters, 2000Elsevier
Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted
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Medicinal Chemistry Letters Volume 10, Issue 6, 20 March 2000, Pages 597-600 Bioorganic &
Medicinal Chemistry Letters Inhibition of inducible nitric oxide synthase by acetamidine
derivatives of hetero-substituted lysine and homolysine Author links open overlay panel Robert …
The synthesis and in vitro evaluation of the acetamidine derivatives of hetero-substituted lysine and homolysine analogues have identified potent inhibitors of human nitric oxide synthase enzymes, including examples with marked selectivity for the inducible isoform.
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