Effects of combined hormone replacement therapy or its effective agents on the IGF-1 pathway in skeletal muscle
E Pöllänen, PHA Ronkainen, M Horttanainen… - Growth Hormone & IGF …, 2010 - Elsevier
OBJECTIVES: To investigate the effects of combined hormone replacement therapy (HRT)
and its effective agents on the IGF-1 signaling pathway. DESIGN AND METHODS: To
examine the effects of HRT on skeletal muscle in vivo, we utilized pre-and post-intervention
samples from a randomized double blinded trial with 50–57-year-old women. The
intervention included the year-long use of either HRT preparation (2mg 17β-estradiol, E2;
1mg norethisterone acetate, NETA, n= 10) or placebo (CO, n= 9). Microarray technology and …
and its effective agents on the IGF-1 signaling pathway. DESIGN AND METHODS: To
examine the effects of HRT on skeletal muscle in vivo, we utilized pre-and post-intervention
samples from a randomized double blinded trial with 50–57-year-old women. The
intervention included the year-long use of either HRT preparation (2mg 17β-estradiol, E2;
1mg norethisterone acetate, NETA, n= 10) or placebo (CO, n= 9). Microarray technology and …