Experimental Zika virus infection induces spinal cord injury and encephalitis in newborn Swiss mice
NCCA Fernandes, JS Nogueira, RA Réssio… - Experimental and …, 2017 - Elsevier
A widespread epidemic of Zika virus (ZIKV) infection was reported in 2015 in South and
Central America, with neurological symptons including meningoencephalitis and Guillain-
Barré syndrome in adults, besides an apparent increased incidence of microcephaly in
infants born to infected mothers. It is becoming a necessity to have a trustworthy animal
model to better understand ZIKV infection. In this study we used newborn white Swiss mice
as a model to investigate the ZIKV strain recently isolated in Brazil. ZIKV was inoculated via …
Central America, with neurological symptons including meningoencephalitis and Guillain-
Barré syndrome in adults, besides an apparent increased incidence of microcephaly in
infants born to infected mothers. It is becoming a necessity to have a trustworthy animal
model to better understand ZIKV infection. In this study we used newborn white Swiss mice
as a model to investigate the ZIKV strain recently isolated in Brazil. ZIKV was inoculated via …