Intrauterine inflammation, insufficient to induce parturition, still evokes fetal and neonatal brain injury

MA Elovitz, AG Brown, K Breen, L Anton… - International Journal of …, 2011 - Elsevier
Exposure to prenatal inflammation is a known risk factor for long term neurobehavioral
disorders including cerebral palsy, schizophrenia, and autism. Models of systemic
inflammation during pregnancy have demonstrated an association with an immune
response an adverse neurobehavioral outcomes for the exposed fetus. Yet, the most
common route for an inflammatory exposure to a fetus is from intrauterine inflammation as
occurs with chorioamnionitis. The aims of this study were to assess the effect of intrauterine …