Inflammatory response and oxidative stress in developing rat brain and its consequences on motor behavior following maternal administration of LPS and perinatal …
F Stigger, G Lovatel, M Marques, K Bertoldi… - International Journal of …, 2013 - Elsevier
Cerebral palsy (CP) is a disorder of locomotion, posture and movement that can be caused
by prenatal, perinatal or postnatal insults during brain development. An increased incidence
of CP has been correlated to perinatal asphyxia and maternal infections during gestation.
The effects of maternal exposure to low doses of bacterial endotoxin (lipopolysaccharide,
LPS) associated or not with perinatal anoxia (PA) in oxidative and inflammatory parameters
were examined in cerebral cortices of newborns pups. Concentrations of TNF-α, IL-1, IL-4 …
by prenatal, perinatal or postnatal insults during brain development. An increased incidence
of CP has been correlated to perinatal asphyxia and maternal infections during gestation.
The effects of maternal exposure to low doses of bacterial endotoxin (lipopolysaccharide,
LPS) associated or not with perinatal anoxia (PA) in oxidative and inflammatory parameters
were examined in cerebral cortices of newborns pups. Concentrations of TNF-α, IL-1, IL-4 …