Changes in endovascular trophoblast invasion and spiral artery remodelling at term in a transgenic preeclamptic rat model
N Geusens, L Hering, S Verlohren, C Luyten… - Placenta, 2010 - Elsevier
As a follow-up to our previous study which revealed a surprisingly deeper endovascular
trophoblast (ET) invasion on day 18 in a transgenic preeclamptic (PE) rat model
(hAngiotensinogen♀× hRenin♂) compared to non-PE controls, we examined further
changes in ET invasion and associated spiral artery (SA) remodelling at term (day 21). PE
transgenic rats and non-PE reversely mated (RM) transgenic rats were compared to normal
SD rats (C). Sections were stained to visualize trophoblast, fibrinoid, vascular smooth …
trophoblast (ET) invasion on day 18 in a transgenic preeclamptic (PE) rat model
(hAngiotensinogen♀× hRenin♂) compared to non-PE controls, we examined further
changes in ET invasion and associated spiral artery (SA) remodelling at term (day 21). PE
transgenic rats and non-PE reversely mated (RM) transgenic rats were compared to normal
SD rats (C). Sections were stained to visualize trophoblast, fibrinoid, vascular smooth …