Clinical utility of serum beta-2-microglobulin as a predictor of diabetic complications in patients with type 2 diabetes without renal impairment
Aim As serum beta-2-microglobulin (B2M) levels are usually elevated in patients with renal
failure, they have been suggested as a surrogate marker of cardiovascular mortality for
patients with chronic kidney disease. Glycation of B2M is cytotoxic and may contribute to the
risk of diabetic complications in patients with diabetes. Our objective was to evaluate the
relationship between B2M and diabetic complications in patients with type 2 diabetes (T2D)
and normal kidney function. Methods A total of 366 patients with T2D and preserved renal …
failure, they have been suggested as a surrogate marker of cardiovascular mortality for
patients with chronic kidney disease. Glycation of B2M is cytotoxic and may contribute to the
risk of diabetic complications in patients with diabetes. Our objective was to evaluate the
relationship between B2M and diabetic complications in patients with type 2 diabetes (T2D)
and normal kidney function. Methods A total of 366 patients with T2D and preserved renal …
