Risk of diabetic ketoacidosis after initiation of an SGLT2 inhibitor

M Fralick, S Schneeweiss… - New England Journal of …, 2017 - Mass Medical Soc
M Fralick, S Schneeweiss, E Patorno
New England Journal of Medicine, 2017Mass Medical Soc
Risk of Diabetic Ketoacidosis after Initiation of an SGLT2 Inhibitor Page 1 Correspondence The
new england journal of medicine n engl j med 376;23 nejm.org June 8, 2017 2300
Correspondence Risk of Diabetic Ketoacidosis after Initiation of an SGLT2 Inhibitor To the
Editor: Inhibitors of sodium–glucose cotransporter 2 (SGLT2) decrease plasma glucose by
blocking the reabsorption of glucose at the proximal tubule.Case reports have suggested that
SGLT2 inhibitors may be associated with an increased risk of diabetic ketoacidosis, which led …
A study that assessed the risk of diabetic ketoacidosis after the initiation of SGLT2 inhibitor therapy showed nearly twice the risk as with a DPP4 inhibitor.
The New England Journal Of Medicine