Glycogen autophagy in glucose homeostasis

OB Kotoulas, SA Kalamidas… - Pathology-Research and …, 2006 - Elsevier
Glycogen autophagy, the sequestration and degradation of cell glycogen in the autophagic
vacuoles, is a selective, hormonally controlled and highly regulated process, representing a
mechanism of glucose homeostasis under conditions of demand for the production of this
sugar. In the newborn animals, this process is induced by glucagon secreted during the
postnatal hypoglycemia and inhibited by insulin and parenteral glucose, which abolishes
glucagon secretion. Hormonal action is mediated by the cAMP/protein kinase A (induction) …