Differential agglutination of normal and sensitized sheep erythrocytes by sera of patients with rheumatoid arthritis

HM Rose, C Ragan, E Pearce… - Proceedings of the …, 1948 - journals.sagepub.com
HM Rose, C Ragan, E Pearce, MO Lipman
Proceedings of the Society for Experimental Biology and Medicine, 1948journals.sagepub.com
A differential sheep cell agglutination test is described wherein the agglutination titers of
human serum for normal and sensitized sheep erythrocytes are compared. High differential
titers have been found to occur almost solely with the sera of patients suffering from active
rheumatoid arthritis. Some of the features of this serological phenomenon are pointed out,
together with its possible practical applications.
Summary
A differential sheep cell agglutination test is described wherein the agglutination titers of human serum for normal and sensitized sheep erythrocytes are compared. High differential titers have been found to occur almost solely with the sera of patients suffering from active rheumatoid arthritis. Some of the features of this serological phenomenon are pointed out, together with its possible practical applications.
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