Effect of fatty acids on the growth of Corynebacterium acnes in vitro

SM Puhvel, RM Reisner - Journal of Investigative Dermatology, 1970 - Elsevier
SM Puhvel, RM Reisner
Journal of Investigative Dermatology, 1970Elsevier
Seven saturated and three unsaturated fatty acids were tested in ten different concentrations
(from 0.5 mcg to 500 mcg/ml of medium) for their effect on the growth of Corynebacterium
acnes in vitro. Of the unsaturated fatty acids tested, oleic acid (18: 1) was found to
significantly stimulate C. acnes growth. Saturated fatty acids from C 8 to C 16 were found to
suppress C. acnes growth. Lauric acid (12: 0) was the most inhibitory. These findings are
discussed in relation to the in vivo ecology of the human skin flora.
Seven saturated and three unsaturated fatty acids were tested in ten different concentrations (from 0.5 mcg to 500 mcg/ml of medium) for their effect on the growth of Corynebacterium acnes in vitro. Of the unsaturated fatty acids tested, oleic acid (18: 1) was found to significantly stimulate C. acnes growth. Saturated fatty acids from C8 to C16 were found to suppress C. acnes growth. Lauric acid (12:0) was the most inhibitory. These findings are discussed in relation to the in vivo ecology of the human skin flora.
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