Common variable immunodeficiency: association between memory B cells and lung diseases
D Detková, J de Gracia, S Lopes-da-Silva, M Vendrell… - Chest, 2007 - Elsevier
Background Malabsorption syndrome often develops in patients with common variable
immunodeficiency (CVID). Why structural damages appear in some CVID patients and not in
others is not fully understood. Memory B cells (MBs) are responsible for the production of
specific antibodies, and their defects have previously been related to autoimmune,
granulomatous, and lymphoproliferative complications of CVID. The objective of this study
was to ascertain whether a relationship exists between MB defects and the clinical outcome …
immunodeficiency (CVID). Why structural damages appear in some CVID patients and not in
others is not fully understood. Memory B cells (MBs) are responsible for the production of
specific antibodies, and their defects have previously been related to autoimmune,
granulomatous, and lymphoproliferative complications of CVID. The objective of this study
was to ascertain whether a relationship exists between MB defects and the clinical outcome …