Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population
MAI Mirza, A Larsson, H Melhus, L Lind, TE Larsson - Atherosclerosis, 2009 - Elsevier
Fibroblast growth factor-23 (FGF23) is a hormonal regulator of circulating phosphate and
vitamin D levels. Serum FGF23 is elevated in chronic kidney disease (CKD) and is a
prognostic marker of poor outcomes, such as faster CKD progression and increased
mortality in hemodialysis patients. Despite the high prevalence of cardiovascular disease in
CKD, the relation between circulating FGF23 and cardiovascular risk factors, both in CKD
and in the community, has not been studied in detail. We evaluated the relation between …
vitamin D levels. Serum FGF23 is elevated in chronic kidney disease (CKD) and is a
prognostic marker of poor outcomes, such as faster CKD progression and increased
mortality in hemodialysis patients. Despite the high prevalence of cardiovascular disease in
CKD, the relation between circulating FGF23 and cardiovascular risk factors, both in CKD
and in the community, has not been studied in detail. We evaluated the relation between …