Age-related changes in the static and dynamic mechanical properties of mouse lungs
T Hirai, M Hosokawa, K Kawakami, Y Takubo… - Respiration …, 1995 - Elsevier
To investigate the effects of aging on pulmonary mechanical properties in mice, we devised
a new experimental apparatus to measure the respiratory impedance of excised lungs in
mice and examined age-related changes in both static and dynamic properties. In an
accelerated senescence-resistant strain of mice, SAMR1 (Takeda, T., Y. Fukuchi, Y. Uejima,
K. Teramoto, T. Oka and H. Orino, J. Am. Geriatr. Soc. 39: 911–919, 1991), ranging from 3 to
24 months of age, static compliance (Cst) as well as total lung capacity increased …
a new experimental apparatus to measure the respiratory impedance of excised lungs in
mice and examined age-related changes in both static and dynamic properties. In an
accelerated senescence-resistant strain of mice, SAMR1 (Takeda, T., Y. Fukuchi, Y. Uejima,
K. Teramoto, T. Oka and H. Orino, J. Am. Geriatr. Soc. 39: 911–919, 1991), ranging from 3 to
24 months of age, static compliance (Cst) as well as total lung capacity increased …