[HTML][HTML] Interaction of serum 70-kDa heat shock protein levels and HspA1B (+ 1267) gene polymorphism with disease severity in patients with chronic heart failure
T Gombos, Z Förhécz, Z Pozsonyi, L Jánoskuti… - Cell Stress and …, 2008 - Elsevier
Background Circulating heat shock protein 70 (Hsp70) is present in the circulation of healthy
individuals and in patients with various disorders, including chronic heart failure (CHF).
However, the source and routes of release of Hsp70 is only partially characterised in clinical
samples. Aims The purpose of this study was to study the clinical and biological correlates of
Hsp70 in a CHF population and, for the first time, to investigate the association of HspA1B
(also known as Hsp70-2)+ 1267 alleles with serum Hsp70 levels. Methods A total of 167 …
individuals and in patients with various disorders, including chronic heart failure (CHF).
However, the source and routes of release of Hsp70 is only partially characterised in clinical
samples. Aims The purpose of this study was to study the clinical and biological correlates of
Hsp70 in a CHF population and, for the first time, to investigate the association of HspA1B
(also known as Hsp70-2)+ 1267 alleles with serum Hsp70 levels. Methods A total of 167 …