Aseptic loosening of a knee prosthesis as imaged on FDG positron emission tomography

F De Winter, C Van De Wiele, D De Clercq… - Clinical nuclear …, 2000 - journals.lww.com
FDG positron emission tomography (PET) has been presented as a highly accurate
technique (n= 51; accuracy 96%, no false-positive results) for diagnosing chronic
osteomyelitis. The authors report a case of high FDG uptake in aseptic loosening of a knee
prosthesis. The FDG uptake mechanism in infection is related to increased tracer
accumulation in activated macrophages, leukocytes, and fibroblasts. Macrophages and
fibroblasts also play a role in aseptic loosening. This may be reflected in an elevated FDG …