Inflammatory gene expression in whole blood cells after EPA vs. DHA supplementation: Results from the ComparED study
C Vors, J Allaire, J Marin, MC Lépine, A Charest… - Atherosclerosis, 2017 - Elsevier
Background and aims Whether EPA and DHA exert similar anti-inflammatory effects through
modulation of gene expression in immune cells remains unclear. The aim of the study was to
compare the impact of EPA and DHA supplementation on inflammatory gene expression in
subjects at risk for cardiometabolic diseases. Methods In this randomized double-blind
crossover trial, 154 men and women with abdominal obesity and low-grade inflammation
were subjected to three 10-wk supplementation phases: 1) EPA (2.7 g/d); 2) DHA (2.7 g/d); …
modulation of gene expression in immune cells remains unclear. The aim of the study was to
compare the impact of EPA and DHA supplementation on inflammatory gene expression in
subjects at risk for cardiometabolic diseases. Methods In this randomized double-blind
crossover trial, 154 men and women with abdominal obesity and low-grade inflammation
were subjected to three 10-wk supplementation phases: 1) EPA (2.7 g/d); 2) DHA (2.7 g/d); …