Intraamniotic infection with fusobacteria

W Chaim, M Mazor - Archives of gynecology and obstetrics, 1992 - Springer
W Chaim, M Mazor
Archives of gynecology and obstetrics, 1992Springer
A literature search produced ten studies in which Fusobacterium was cultured from amniotic
fluid in women with preterm labor and intact membranes or with preterm premature rupture
of membranes (PROM). Fusobacterium was isolated in 9.9%(9/91) of positive amniotic fluid
cultures in women with preterm PROM and in 28.3%(17/60) of positive amniotic fluid
cultures in women presenting with preterm labor and intact membranes. Fusobacterium
plays a previously unrecognized role in the pathogenesis of premature labor and delivery …
Summary
A literature search produced ten studies in which Fusobacterium was cultured from amniotic fluid in women with preterm labor and intact membranes or with preterm premature rupture of membranes (PROM). Fusobacterium was isolated in 9.9% (9/91) of positive amniotic fluid cultures in women with preterm PROM and in 28.3% (17/60) of positive amniotic fluid cultures in women presenting with preterm labor and intact membranes. Fusobacterium plays a previously unrecognized role in the pathogenesis of premature labor and delivery. Amniotic fluid culture for anaerobs, specifically Fusobacterium, is suggested for all women who present with premature labor and intact membranes and do not respond to tocolytic drugs.
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