Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes.
Accordingly, chemokines are remarkably pleiotropic molecules involved in a range of
physiological as well as pathological processes. For example, the CXCR3 chemokine
receptor is expressed on activated T lymphocytes, dendritic cells and natural killer cells, but
also fibroblasts and smooth muscle, epithelial and endothelial cells. In men, these cells …