[HTML][HTML] Dysfunctional phenotypes of CD4+ and CD8+ T cells are comparable in patients initiating ART during early or chronic HIV-1 infection
S Amu, RL Graham, Y Bekele, A Nasi, C Bengtsson… - Medicine, 2016 - journals.lww.com
Early initiation of antiretroviral therapy (ART) is becoming a common clinical practice
according to current guidelines recommending treatment to all HIV-1-infected patients.
However, it is not known whether ART initiated during the early phase of infection prevents
the establishment of abnormal phenotypic features previously reported in CD4+ and CD8+ T
cells during chronic HIV-1 infection. In this cross-sectional study, blood specimens were
obtained from 17 HIV-1-infected patients who began ART treatment shortly after infection …
according to current guidelines recommending treatment to all HIV-1-infected patients.
However, it is not known whether ART initiated during the early phase of infection prevents
the establishment of abnormal phenotypic features previously reported in CD4+ and CD8+ T
cells during chronic HIV-1 infection. In this cross-sectional study, blood specimens were
obtained from 17 HIV-1-infected patients who began ART treatment shortly after infection …