[HTML][HTML] Differing rates of cholesterol absorption among inbred mouse strains yield differing levels of HDL-cholesterol
TJ Sontag, B Chellan, GS Getz, CA Reardon - Journal of Lipid Research, 2013 - ASBMB
Inbred strains of mice with differing susceptibilities to atherosclerosis possess widely varying
plasma HDL levels. Cholesterol absorption and lipoprotein formation were compared
between atherosclerosis-susceptible, low-HDL C57BL6/J mice and atherosclerosis-
resistant, high-HDL FVBN/J mice.[3 H] cholesterol and triglyceride appeared in the plasma
of FVB mice gavaged with cholesterol in olive oil at a much higher rate than in C57 mice.
The plasma cholesterol was found almost entirely as HDL-cholesterol in both strains …
plasma HDL levels. Cholesterol absorption and lipoprotein formation were compared
between atherosclerosis-susceptible, low-HDL C57BL6/J mice and atherosclerosis-
resistant, high-HDL FVBN/J mice.[3 H] cholesterol and triglyceride appeared in the plasma
of FVB mice gavaged with cholesterol in olive oil at a much higher rate than in C57 mice.
The plasma cholesterol was found almost entirely as HDL-cholesterol in both strains …