The nephron is the functional unit of the kidney, but the mechanism of nephron formation
during human development is unclear. We conducted a detailed analysis of nephron
development in humans and mice by immunolabeling, and we compared human and mouse
nephron patterning to describe conserved and divergent features. We created protein
localization maps that highlight the emerging patterns along the proximal–distal axis of the
developing nephron and benchmark expectations for localization of functionally important …