[HTML][HTML] Parabiosis reveals leukocyte dynamics in the kidney
JM Lever, Z Yang, R Boddu, OO Adedoyin, L Guo… - Laboratory …, 2018 - Elsevier
The immune cellular compartment of the kidney is involved in organ development and
homeostasis, as well as in many pathological conditions. Little is known about the
mechanisms that drive intrarenal immune responses in the presence of renal tubular and
interstitial cell death. However, it is known that tissue-resident leukocytes have the potential
to have distinct roles compared with circulating cells. We used a parabiosis model in
C57BL/6 CD45 congenic and green fluorescent protein transgenic mice to better understand …
homeostasis, as well as in many pathological conditions. Little is known about the
mechanisms that drive intrarenal immune responses in the presence of renal tubular and
interstitial cell death. However, it is known that tissue-resident leukocytes have the potential
to have distinct roles compared with circulating cells. We used a parabiosis model in
C57BL/6 CD45 congenic and green fluorescent protein transgenic mice to better understand …