Inflammation is a complex biologic response that is essential for eliminating microbial
pathogens and repairing tissue after injury. AKI associates with intrarenal and systemic
inflammation; thus, improved understanding of the cellular and molecular mechanisms
underlying the inflammatory response has high potential for identifying effective therapies to
prevent or ameliorate AKI. In the past decade, much knowledge has been generated about
the fundamental mechanisms of inflammation. Experimental work in small animal models …