The effect of mycophenolic acid on epigenetic modifications in lupus CD4+ T cells
Y Yang, Q Tang, M Zhao, G Liang, H Wu, D Li, Y Xie… - Clinical …, 2015 - Elsevier
Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease involving
multiple organs and characterized by overproduction of autoantibodies and T and B cell
abnormalities. The treatment for SLE has been restricted to immunosuppressants and
corticosteroids. Mycophenolate mofetil (MMF), as a relatively new immunosuppressant, is
now widely used in the treatment of SLE patients, particularly those with nephritis. However,
it is unclear whether mycophenolic acid (MPA) could modulate the reported disorders of …
multiple organs and characterized by overproduction of autoantibodies and T and B cell
abnormalities. The treatment for SLE has been restricted to immunosuppressants and
corticosteroids. Mycophenolate mofetil (MMF), as a relatively new immunosuppressant, is
now widely used in the treatment of SLE patients, particularly those with nephritis. However,
it is unclear whether mycophenolic acid (MPA) could modulate the reported disorders of …