BiNGO: a Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks
The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to
determine which Gene Ontology (GO) terms are significantly overrepresented in a set of
genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on
subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant
functional themes of the tested gene set on the GO hierarchy, and takes advantage of
Cytoscape's versatile visualization environment to produce an intuitive and customizable …
determine which Gene Ontology (GO) terms are significantly overrepresented in a set of
genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on
subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant
functional themes of the tested gene set on the GO hierarchy, and takes advantage of
Cytoscape's versatile visualization environment to produce an intuitive and customizable …
Abstract
Summary: The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape's versatile visualization environment to produce an intuitive and customizable visual representation of the results.
Availability: http://www.psb.ugent.be/cbd/papers/BiNGO/
Contact: martin.kuiper@psb.ugent.be
Oxford University Press