Chromosomal anomalies in stage D1 prostate adenocarcinoma primary tumors and lymph node metastases detected by fluorescence in situ hybridization
BM Gburek, TA Kollmorgen, J Qian… - The Journal of …, 1997 - Elsevier
PURPOSE: We determined if characteristic chromosomal anomalies exist within the primary
tumors and lymph node metastases in patients with stage D1 prostate cancer, and
compared the patterns of chromosomal alterations between primary tumors and nodal
metastases. MATERIALS AND METHODS: Fluorescence in situ hybridization analysis using
peri-centromeric probes for chromosomes 6, 7, 8, 17, X and Y was performed on 5 micro.
sections from paraffin embedded tissue blocks obtained from 23 consecutive patients who …
tumors and lymph node metastases in patients with stage D1 prostate cancer, and
compared the patterns of chromosomal alterations between primary tumors and nodal
metastases. MATERIALS AND METHODS: Fluorescence in situ hybridization analysis using
peri-centromeric probes for chromosomes 6, 7, 8, 17, X and Y was performed on 5 micro.
sections from paraffin embedded tissue blocks obtained from 23 consecutive patients who …