Effect of aspirin on development of ARDS in at-risk patients presenting to the emergency department: the LIPS-A randomized clinical trial
Importance Management of acute respiratory distress syndrome (ARDS) remains largely
supportive. Whether early intervention can prevent development of ARDS remains unclear.
Objective To evaluate the efficacy and safety of early aspirin administration for the
prevention of ARDS. Design, Setting, and Participants A multicenter, double-blind, placebo-
controlled, randomized clinical trial conducted at 16 US academic hospitals. Between
January 2, 2012, and November 17, 2014, 7673 patients at risk for ARDS (Lung Injury …
supportive. Whether early intervention can prevent development of ARDS remains unclear.
Objective To evaluate the efficacy and safety of early aspirin administration for the
prevention of ARDS. Design, Setting, and Participants A multicenter, double-blind, placebo-
controlled, randomized clinical trial conducted at 16 US academic hospitals. Between
January 2, 2012, and November 17, 2014, 7673 patients at risk for ARDS (Lung Injury …