Randomized clinical trial of a combination of an inhaled corticosteroid and beta agonist in patients at risk of developing the acute respiratory distress syndrome
E Festic, GE Carr, R Cartin-Ceba, RF Hinds… - Critical care …, 2017 - journals.lww.com
Objectives: Effective pharmacologic treatments directly targeting lung injury in patients with
the acute respiratory distress syndrome are lacking. Early treatment with inhaled
corticosteroids and beta agonists may reduce progression to acute respiratory distress
syndrome by reducing lung inflammation and enhancing alveolar fluid clearance. Design:
Double-blind, randomized clinical trial (ClinicalTrials. gov: NCT01783821). The primary
outcome was longitudinal change in oxygen saturation divided by the F io 2 (S/F) through …
the acute respiratory distress syndrome are lacking. Early treatment with inhaled
corticosteroids and beta agonists may reduce progression to acute respiratory distress
syndrome by reducing lung inflammation and enhancing alveolar fluid clearance. Design:
Double-blind, randomized clinical trial (ClinicalTrials. gov: NCT01783821). The primary
outcome was longitudinal change in oxygen saturation divided by the F io 2 (S/F) through …