Cytomegalovirus reactivation is associated with a lower rate of early relapse in myeloid malignancies independent of in-vivo T cell depletion strategy
T Hilal, S Slone, S Peterson, C Bodine, Z Gul - Leukemia Research, 2017 - Elsevier
The association between cytomegalovirus (CMV) reactivation and relapse risk has not been
evaluated in relation to T cell depletion strategies. We evaluated 93 patients who underwent
allogeneic hematopoietic stem cell transplantation (HSCT) and analyzed the association
between T cell depletion strategies with the cumulative incidence of relapse and CMV
reactivation. A total of 33% of patients who received ATG vs. 34% who received
alemtuzumab developed CMV reactivation. The cumulative incidence of relapse was 3% at …
evaluated in relation to T cell depletion strategies. We evaluated 93 patients who underwent
allogeneic hematopoietic stem cell transplantation (HSCT) and analyzed the association
between T cell depletion strategies with the cumulative incidence of relapse and CMV
reactivation. A total of 33% of patients who received ATG vs. 34% who received
alemtuzumab developed CMV reactivation. The cumulative incidence of relapse was 3% at …