Injury to the spinal cord results in direct damage to axons, neuronal cell bodies, and glia that
cause functional loss below the site of injury. In addition, the injury also triggers an
inflammatory response that contributes to secondary tissue damage that leads to further
functional loss. Reducing inflammation after spinal cord injury (SCI) is therefore a worthy
therapeutic goal. Inflammation in the injured spinal cord is a complex response that involves
resident cells of the central nervous system as well as infiltrating immune cells, and is …