Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of …
JS Orange, EM Hossny, CR Weiler, M Ballow… - Journal of Allergy and …, 2006 - Elsevier
Human immunoglobulin prepared for intravenous administration (IGIV) has a number of
important uses in the treatment of disease. Some of these are in diseases for which
acceptable treatment alternatives do not exist. In this review we have evaluated the
evidence underlying a wide variety of IGIV uses and make specific recommendations on the
basis of these data. Given the potential risks and inherent scarcity of IGIV, careful
consideration of the indications for and administration of IGIV is warranted.
important uses in the treatment of disease. Some of these are in diseases for which
acceptable treatment alternatives do not exist. In this review we have evaluated the
evidence underlying a wide variety of IGIV uses and make specific recommendations on the
basis of these data. Given the potential risks and inherent scarcity of IGIV, careful
consideration of the indications for and administration of IGIV is warranted.