Diffusion changes in patients with systemic lupus erythematosus

L Zhang, M Harrison, LA Heier, RD Zimmerman… - Magnetic resonance …, 2007 - Elsevier
BACKGROUND AND PURPOSE: Systemic lupus erythematosus (SLE) is an autoimmune
disease in which almost all the organs are involved. Neuropsychiatric SLE is of one of the
major concerns in the clinical evaluation of this disease. Routine magnetic resonance
imaging (MRI) findings are often nonspecific or negative. In this study, we explored the use
of diffusion tensor imaging in assisting with the diagnosis of SLE. METHODS: Data from 34
SLE patients (age range, 18–73 years) and 29 age-matched volunteers (age range, 29–64 …