Background Alzheimer's disease (AD) and Parkinson's disease (PD) are the two common
neurodegenerative diseases characterized by progressive neuronal dysfunction in the
presence of pathological microglial activation. Methods 10 AD, 10 mild cognitive impairment
(MCI), 11 PD dementia (PDD), and 16 controls underwent magnetic resonance
imaging,[11C](R) PK11195 (1-[2-chlorophenyl]-N-methyl-N-[1-methyl-propyl]-3-isoquinoline
carboxamide),[11C] PIB (11C-Pittsburgh compound B),[18F] FDG-PET (18F-2-fluoro-2 …