[HTML][HTML] Apoptosis induced in vitro and in vivo during infection by Ebola and Marburg viruses
TW Geisbert, LE Hensley, TR Gibb, KE Steele… - Laboratory …, 2000 - Elsevier
Induction of apoptosis has been documented during infection with a number of different
viruses. In this study, we used transmission electron microscopy (TEM) and terminal
deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling to
investigate the effects of Ebola and Marburg viruses on apoptosis of different cell
populations during in vitro and in vivo infections. Tissues from 18 filovirus-infected
nonhuman primates killed in extremis were evaluated. Apoptotic lymphocytes were seen in …
viruses. In this study, we used transmission electron microscopy (TEM) and terminal
deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling to
investigate the effects of Ebola and Marburg viruses on apoptosis of different cell
populations during in vitro and in vivo infections. Tissues from 18 filovirus-infected
nonhuman primates killed in extremis were evaluated. Apoptotic lymphocytes were seen in …