Mechanisms underlying the neuronal-based symptoms of allergy

BJ Undem, T Taylor-Clark - Journal of allergy and clinical immunology, 2014 - Elsevier
Persons with allergies present with symptoms that often are the result of alterations in the
nervous system. Neuronally based symptoms depend on the organ in which the allergic
reaction occurs but can include red itchy eyes, sneezing, nasal congestion, rhinorrhea,
coughing, bronchoconstriction, airway mucus secretion, dysphagia, altered gastrointestinal
motility, and itchy swollen skin. These symptoms occur because mediators released during
an allergic reaction can interact with sensory nerves, change processing in the central …