Lifetime prevalence of major depression and its effect on treatment outcome in obese type II diabetic patients

MD Marcus, RR Wing, J Guare, EH Blair… - Diabetes …, 1992 - Am Diabetes Assoc
MD Marcus, RR Wing, J Guare, EH Blair, A Jawad
Diabetes care, 1992Am Diabetes Assoc
Objective—To assess the lifetime prevalence of major depression (MD) and its relation to
glycemic control among a group of non-insulin-dependent (type II) diabetic subjects seeking
obesity treatment and to determine whether a history of MD affected response to treatment.
Research Design and Methods—Sixty-six obese subjects with type II diabetes (22 men, 44
women) completed the Inventory to Diagnose Depression-Lifetime Version before a 52-wk
behavioral weight-control program. Weight, glycosylated hemoglobin, fasting blood glucose …
Objective
— To assess the lifetime prevalence of major depression (MD) and its relation to glycemic control among a group of non-insulin-dependent (type II) diabetic subjects seeking obesity treatment and to determine whether a history of MD affected response to treatment.
Research Design and Methods
— Sixty-six obese subjects with type II diabetes (22 men, 44 women) completed the Inventory to Diagnose Depression-Lifetime Version before a 52-wk behavioral weight-control program. Weight, glycosylated hemoglobin, fasting blood glucose, and mood were assessed at pre-and posttreatment.
Results
— Thirty-two percent of the subjects reported a history of MD. Neither a history of MD nor current depressive symptoms were associated with pretreatment glycemic control. However, a history of MD was related to treatment attrition (52.4 vs. 22.2%, P = 0.03). Subjects with and without a history of MD showed comparable improvements in weight, glycemic control, and mood.
Conclusions
— A history of MD among type II diabetic patients seeking obesity treatment was not related to pretreatment glycemic control but was associated with higher rates of attrition from treatment. Individuals with a history of MD who completed the program did not differ from those with no history of MD in response to treatment.
Am Diabetes Assoc