Cardiovascular disease and ovarian function
AN Kallen, L Pal - Current Opinion in Obstetrics and Gynecology, 2011 - journals.lww.com
AN Kallen, L Pal
Current Opinion in Obstetrics and Gynecology, 2011•journals.lww.comOvarian hormones modulate the processes of atherosclerosis and the mechanisms
underlying CHD. The female reproductive hormones offer a cardioprotective milieu that is
rapidly attenuated with the cessation of ovarian function (be it following natural menopause
or after medical or surgical ovarian extirpation). The role of exogenous hormone therapy,
and the nuances of timing and duration of exposure, are still being elucidated.
underlying CHD. The female reproductive hormones offer a cardioprotective milieu that is
rapidly attenuated with the cessation of ovarian function (be it following natural menopause
or after medical or surgical ovarian extirpation). The role of exogenous hormone therapy,
and the nuances of timing and duration of exposure, are still being elucidated.
Summary
Ovarian hormones modulate the processes of atherosclerosis and the mechanisms underlying CHD. The female reproductive hormones offer a cardioprotective milieu that is rapidly attenuated with the cessation of ovarian function (be it following natural menopause or after medical or surgical ovarian extirpation). The role of exogenous hormone therapy, and the nuances of timing and duration of exposure, are still being elucidated.
Lippincott Williams & Wilkins