[HTML][HTML] Type-I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors
RF Foronjy, CC Taggart, AJ Dabo, S Weldon… - Mucosal …, 2015 - Elsevier
The role of proteases in viral infection of the lung is poorly understood. Thus, we examined
matrix metalloproteinases (MMPs) and cathepsin proteases in respiratory syncytial virus
(RSV)-infected mouse lungs. RSV-induced gene expression for MMPs-2,-3,-7,-8,-9,-10,-12,-
13,-14,-16,-17,-19,-20,-25,-27, and-28 and cathepsins B, C, E, G, H, K, L1, S, W, and Z in the
airways of Friend leukemia virus B sensitive strain mice. Increased proteases were present
in the bronchoalveolar lavage fluid (BALF) and lung tissue during infection. Mitochondrial …
matrix metalloproteinases (MMPs) and cathepsin proteases in respiratory syncytial virus
(RSV)-infected mouse lungs. RSV-induced gene expression for MMPs-2,-3,-7,-8,-9,-10,-12,-
13,-14,-16,-17,-19,-20,-25,-27, and-28 and cathepsins B, C, E, G, H, K, L1, S, W, and Z in the
airways of Friend leukemia virus B sensitive strain mice. Increased proteases were present
in the bronchoalveolar lavage fluid (BALF) and lung tissue during infection. Mitochondrial …