Variable benefit in neuropsychological function in HIV-infected HAART-treated patients
Neurology, 2006•AAN Enterprises
The authors examined cognitive performance change in 101 individuals with advanced HIV
infection on highly active antiretroviral therapy (HAART), using standard neuropsychological
testing in three visits, over a 27-month-period. Cognitive performance stabilized in a majority
of HIV+ participants over time. A neuroactive HAART regimen was associated with
neuropsychological improvement. Decline occurred in a minority with lower nadir CD4. The
current CD4 count and plasma viral load were not associated with cognitive change.
infection on highly active antiretroviral therapy (HAART), using standard neuropsychological
testing in three visits, over a 27-month-period. Cognitive performance stabilized in a majority
of HIV+ participants over time. A neuroactive HAART regimen was associated with
neuropsychological improvement. Decline occurred in a minority with lower nadir CD4. The
current CD4 count and plasma viral load were not associated with cognitive change.
The authors examined cognitive performance change in 101 individuals with advanced HIV infection on highly active antiretroviral therapy (HAART), using standard neuropsychological testing in three visits, over a 27-month-period. Cognitive performance stabilized in a majority of HIV+ participants over time. A neuroactive HAART regimen was associated with neuropsychological improvement. Decline occurred in a minority with lower nadir CD4. The current CD4 count and plasma viral load were not associated with cognitive change.
American Academy of Neurology