Effect of exenatide on cholecystokinin-induced gallbladder emptying in fasting healthy subjects
J Keller, ME Trautmann, H Haber, L San Tham… - Regulatory peptides, 2012 - Elsevier
Exenatide is a glucagon-like peptide-1 receptor agonist for the treatment of type 2 diabetes
and has been shown to lower blood glucose through multiple mechanisms, including
glucose-dependent insulin secretion, suppression of postprandial glucagon release and
slowing of gastric emptying. The effects of exenatide on biliary motility are unknown. This
study evaluated the effect of a single dose of exenatide on cholecystokinin (CCK)-induced
gallbladder emptying. Healthy subjects participated in this randomized, 2-period, double …
and has been shown to lower blood glucose through multiple mechanisms, including
glucose-dependent insulin secretion, suppression of postprandial glucagon release and
slowing of gastric emptying. The effects of exenatide on biliary motility are unknown. This
study evaluated the effect of a single dose of exenatide on cholecystokinin (CCK)-induced
gallbladder emptying. Healthy subjects participated in this randomized, 2-period, double …