Regulatory B cells—IL-35 and IL-21 regulate the regulators
TF Tedder, WJ Leonard - Nature reviews rheumatology, 2014 - nature.com
TF Tedder, WJ Leonard
Nature reviews rheumatology, 2014•nature.comIL-21 regulates the activity and number of IL-10-producing regulatory B cells (B10 cells) that
modulate immune responses and limit diverse autoimmune diseases. A new study
demonstrates that IL-35 has a similar function. Identifying regulatory circuits that control B10-
cell function in vivo might open the door to future treatments for autoimmune diseases.
modulate immune responses and limit diverse autoimmune diseases. A new study
demonstrates that IL-35 has a similar function. Identifying regulatory circuits that control B10-
cell function in vivo might open the door to future treatments for autoimmune diseases.
IL-21 regulates the activity and number of IL-10-producing regulatory B cells (B10 cells) that modulate immune responses and limit diverse autoimmune diseases. A new study demonstrates that IL-35 has a similar function. Identifying regulatory circuits that control B10-cell function in vivo might open the door to future treatments for autoimmune diseases.
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