Validation and quality control of immunophenotyping in clinical flow cytometry
MA Owens, HG Vall, AA Hurley, SB Wormsley - Journal of immunological …, 2000 - Elsevier
Clinical flow cytometry has evolved from two-parameter quantitative assessment of
peripheral blood lymphocytes to six-parameter qualitative evaluation of bone marrow for
hematopathology. Leukemia and lymphoma immunophenotyping represent an extremely
important complement to morphology in the diagnosis and monitoring of hematopoietic
malignancies. The complexity of five-and six-parameter analyses and the interpretation of
the data rely on standardization and validation of the instrument, the reagents and the …
peripheral blood lymphocytes to six-parameter qualitative evaluation of bone marrow for
hematopathology. Leukemia and lymphoma immunophenotyping represent an extremely
important complement to morphology in the diagnosis and monitoring of hematopoietic
malignancies. The complexity of five-and six-parameter analyses and the interpretation of
the data rely on standardization and validation of the instrument, the reagents and the …